Tuesday, April 30, 2013

Italy's Letta wins confidence vote after pledging growth drive

By James Mackenzie

ROME (Reuters) - Italy's new Prime Minister Enrico Letta won his first vote of confidence in parliament on Monday after promising to press for a change to the European Union's focus on austerity and pursue economic growth and jobs.

Letta said Italy could not afford to focus simply on trying to cut its huge public debt and needed a new emphasis on lifting the economy out of recession.

The confidence motion in his right-left coalition government easily passed as expected, by 453 votes to 153 in the Chamber of Deputies, the lower house.

Letta was backed by his own centre-left Democratic Party (PD), Silvio Berlusconi's centre-right People of Freedom (PDL) party as well as centrists led by former prime minister Mario Monti. The government will be fully empowered after a second vote in the Senate on Tuesday.

However, the first opinion poll published since his cabinet was announced, conducted by the EMG agency, gave Letta an approval rating of just 41 percent, showing that many Italians are unconvinced by the coalition of former adversaries.

Just 13 percent of Italians said they wanted Letta as prime minister, suggesting he may struggle to obtain the honeymoon period usually enjoyed by new governments. Monti began his government with approval ratings as high as 70 percent.

"We will die of fiscal consolidation alone, growth policies cannot wait any longer," Letta said in his speech to the Chamber of Deputies, describing the country's economic situation as still "serious" after more than a decade of stagnation.

POSITIVE REACTION

Financial market reaction to Letta's appointment and the end of months of political stalemate in the euro zone's third largest economy has been positive, with bond yields falling and shares rising.

Italy's cost of borrowing dropped to its lowest since October 2010 at an auction of mid and long term bonds.

Letta, a 46-year-old moderate with strong contacts outside Italy, pledged to stick to Rome's budget commitments to its European Union partners, announcing he would visit Brussels, Paris and Berlin this week.

He joined the growing numbers of European politicians attacking the former consensus on budget austerity but offered few specific proposals about how to restore growth to Italy's economy, which has shrunk below the level it was in 2001.

"We all have the clear and strong feeling that our destiny will be the destiny we want only if the choices Europe makes are different from the choices made up to now," he said.

Stefano Fassina, the PD's main economic spokesman, said Letta should renegotiate Italy's budget target to gain more breathing room. "Other countries have done it and so should we," he said in parliament.

Letta was pushed into a coalition with Berlusconi after the centre-left fell short of a viable parliamentary majority in February's inconclusive election, which left no side with the numbers to govern alone.

Berlusconi, who is fighting legal battles over a tax fraud conviction and charges of paying for sex with a minor, will not be in cabinet but will exercise a powerful influence behind the scenes, to the disgust of many on the left who find the idea of working with their old enemy abhorrent.

POINTS OF CONFLICT

In a speech that ranged from tax to constitutional reform and touched on issues including tourism, prisons and two Italian marines at the centre of a diplomatic standoff with India, Letta avoided points of conflict between members of his coalition.

He made no reference to a law tackling conflicts of interests, which was promised by his PD party before and after the election but would be unacceptable to media tycoon Berlusconi, who has staked a claim to chair a special commission examining institutional reforms.

Responding to centre-right demands for an unpopular housing tax to be scrapped, Letta said payments due in June would be halted although he did not promise to abolish the tax altogether as Berlusconi has demanded.

He hoped a planned increase in sales tax, which would see the main rate rise from 21 percent to 22 percent in July, could be delayed and said payroll taxes that dissuaded companies from hiring should be lowered.

He did not indicate how he would pay for tax changes, which together with proposed measures to extend unemployment protection would require as much as 10 billion euros ($13 billion) in 2013.

The current electoral law, which contributed heavily to the inconclusive election result in February would be changed before the next election and he proposed a special commission to consider other political and constitutional reforms.

(Additional reporting by Catherine Hornby, Gavin Jones, Steve Scherer, Naomi O'Leary; Editing by Giles Elgood)

Source: http://news.yahoo.com/italys-letta-government-begins-life-climate-crisis-050501937.html

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Online poker is back: Legal website launches in NV

(AP) ? Poker devotees will soon be able to skip the smoky casino and legally gamble their dollars away on the couch ? at least in the state of Nevada.

A Las Vegas-based social gambling company is expected to launch the first legal, real-money poker website in the United States on Tuesday morning.

The site, run by Ultimate Gaming, will accept wagers only from players in Nevada for now, but likely represents the shape of things to come for gamblers across the country.

Internet poker, never fully legal, has been strictly outlawed since 2011, when the Department of Justice seized the domain names of the largest offshore sites catering to U.S. customers and blacked them out.

This crackdown, dubbed "black Friday," left poker fanatics with two options: They could either get dressed and visit a visit a card room, or break the law and log into an offshore site.

More recently, the federal government softened its stance on Internet betting, and three states ? New Jersey, Delaware and Nevada? have legalized some form of online wagering within their borders.

With Tuesday's launch, Nevada wins the race to bring Texas Hold 'em back to the Internet.

"There was black Friday, and now we're going to have 'trusting Tuesday,'" said Ultimate Gaming CEO Tobin Prior. "Players won't have to worry if their money is safe. They are going to be able to play with people they can trust and know the highest regulatory standards have been applied."

The site, UltimatePoker.com, will look familiar to anyone who participated in the poker craze of the 2000s. Only the account setup and login process have changed. Instead of checking a box certifying they are older than 18, players will have to endure a lengthy account setup process involving a Social Security number and a Nevada address. Only those older than 21 will be allowed to play.

Ultimate Gaming and the two dozen other companies still fine-tuning their Nevada poker sites hope they will win the trust not only of players, but of regulators and politicians.

"It's an opportunity to show the world how to properly run online poker," Ultimate Gaming chairman Tom Breitling said.

Several cash-hungry states are weighing legislation that would allow them to tap into what is expected to be a multibillion-dollar market. Some bills would legalize only poker, as Nevada has, while others would throw open the gates to all casino games, including slots, as New Jersey and Delaware have done.

Earlier this year, Nevada Gov. Brian Sandoval approved legislation that gives him the ability to sign deals with other governors to facilitate interstate Internet gambling.

Online gamblers around the world currently wager an estimated $35 billion each year, according to the American Gaming Association. A fully realized U.S. online poker market could generate $4.3 billion in revenue its first year, and $9.6 billion by year five, according to London-based research firm H2 Gambling Capital.

Still, with federal efforts to legalize Internet poker stalled, it may be a while before a critical mass of states link together to lure professional players back from overseas and drive up jackpots.

Nevada, a state of just 2.8 million, attracts 47 million visitors a year? more than the population of California. But who wants to go on vacation just to fire up their laptop and play some virtual cards?

"I think the real excitement will be when we get a very populous state like a California or a New York allowing these companies to expand," ITG casino analyst Matthew Jacob said. "But these changes often take longer to occur than people assume. It requires a change in law and then it takes a while from when the law passes until the sites are up and running."

Prior says he intends to make Ultimate Poker profitable within a matter of years, in part through cross-promotion with mixed martial arts giant Ultimate Fighting Championship. The companies share a common owner: Frank Fertitta III and his brother Lorenzo, who also own Station Casinos Inc., an extensive chain that caters to locals in Las Vegas.

The Ultimate Poker logo has enjoyed prime placement in the UFC fight octagon for months. The Ultimate Poker Facebook page, which steers fans to a zero-stakes version of the site, features a mix of UFC glamour shots and stock images of guys in hoodies staring into laptop screens.

"When you look at the demographic of the UFC fan and the online poker player, it's almost a perfect overlap," Breitling said.

In the coming months, Ultimate Gaming will have to prove that its technology and 111 employees can prevent minors and out-of-state players from wagering real dollars, and guard against money laundering.

It will also have to pay 6.75 percent of its revenue in Nevada state taxes.

It's unclear how much of a boon the new market will be to the cash-strapped state. In 2012, the Pew Center on the States analyzed 13 states that had recently legalized new types of gambling, and found that more than two-thirds of "failed to live up to the initial promises or projections."

The gambling industry is hoping the return of Internet poker will revitalize interest in the game and help brick and mortar casinos capture a younger market.

The rise of Internet poker is generally credited with helping spark the poker fad of the last decade. The end of online gambling is thought to have helped quash interest in the game.

In the coming months, the industry will be watching closely to see if poker players come flocking back from their new hobbies, replacement computer games and illegal offshore gambling sites.

"This is a really huge moment for our company, the state of Nevada and the gaming community," Breitling said. "We're hoping to make poker fun again."

___

Hannah Dreier can be reached at http://twitter.com/hannahdreier

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/495d344a0d10421e9baa8ee77029cfbd/Article_2013-04-30-US-Internet-Gambling/id-05ce886ec7a3432eb52e6e878fb8219e

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Yahoo announces six original shows, WWE streaming partnership

Yahoo announces six original shows, WWE streaming partnership

It's been just under a week since Yahoo scored exclusive rights to stream Saturday Night Live clips, but the old guard of search has just divulged more of its video plans at its Digital Content NewFront event. Taking a page from Netflix's playbook, the firm announced its original comedy lineup will be released in a "binge-viewing" style á la House of Cards this fall, and added Tiny Commando, We Need Help and Losing Your Virginity with John Stamos to its humor roster. Mayer and Co. also revealed a trio of lifestyle programs called Fashion Recipe, Cinema & Spice and Grill Girls, which are headed online at some point later this year.

In addition to its in-house programming, Yahoo's partnered with the WWE to create an online wrestling hub starting this summer, which will include clips, a 30-minute Monday Night Raw pre-show, two original weekly shows with 50 episodes per year, an archive of full historic matches and more. The folks in Sunnyvale are also set to stream video content from Conde Nast Entertainment, and expand their relationship with ABC News thanks to World News Behind the Headlines, Nightline: Online and GMA Live. News junkies will also be able to tune into the CNBC's Talking Numbers. For descriptions of the outfit's original shows -- and how it'd like to catch your attention with ads -- hit the jump for the full press release.

[Image credit: Yodel Anecdotal, Flickr]

Comments

Source: Yahoo

Source: http://feeds.engadget.com/~r/weblogsinc/engadget/~3/DHzLSkIoImE/

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Monday, April 29, 2013

Fire destroys Danish museum, collection saved

COPENHAGEN, Denmark (AP) ? A fire blazed through The Museum of Danish Resistance in Copenhagen on Sunday, destroying large parts of the building but most of the collection was saved, museum officials said.

No one was injured in the fire and firefighters and staff who rushed to the scene in central Copenhagen managed to save the majority of display items, museum spokesman Henrik Schilling said.

The fire started in the museum cafe around 2 a.m. and quickly spread to the exhibition hall. The last pockets of fire were being extinguished shortly after noon, Schilling said.

The museum is an affiliate of the Danish National Museum and exhibits objects related to the Danish resistance to the German occupation during World War II. The wooden building, located close to the waterfront, was built specifically for its purpose in the 1950s, Schilling said.

Nazi Germany's occupation of Denmark started on April 9, 1940, and continued until the Germans surrendered to the Allies on May 5, 1945. The Danish resistance movement distributed illegal flyers and upheld secret radio communication with the British. The resistance grew stronger toward the end of the war, when acts of violent sabotage against factories and railways increased.

The cause of the fire is not yet known. Schilling said it is still unclear if the building can be restored or needs to be rebuilt entirely.

Source: http://news.yahoo.com/fire-destroys-danish-museum-collection-saved-112137703.html

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Sunday, April 28, 2013

Sponsor Me

I'm quite interested in joining, but I'd like to wait and see what other people join as so I can fill in whatever you're lacking in later on. Plus it's late where I am, and I need some sleep.

I'll keep watch for awhile and decide my race later. =P

Cool idea about the vampires feeding off of different things, by the way.

Source: http://feedproxy.google.com/~r/RolePlayGateway/~3/cJB8yfjkUkY/viewtopic.php

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Moody's, S&P settle lawsuits over debt ratings

NEW YORK (AP) ? Ratings agencies Standard & Poor's, Moody's and investment bank Morgan Stanley have settled two lawsuits dating back to the financial crisis that accused them of hiding risky investments.

The lawsuits from King County in Washington state and Abu Dhabi Commercial Bank claimed that the ratings agencies and Morgan Stanley hid the risk of investing in a fund that purchased bonds backed by subprime mortgages.

Judge Shira Scheindlin dismissed the lawsuits on Friday, in federal court in New York, with prejudice, which means they can't be filed again.

Spokesmen for the McGraw-Hill Cos., which owns S&P, Moody's Corp. and Morgan Stanley confirmed the settlements but did not disclose terms.

"This settlement allows us to put the significant legal defense and related costs, as well as the distraction, of these very protracted litigations behind us," said Moody's spokesman Michael Adler in an emailed statement. "We are satisfied that it is in the best interests of our company and shareholders."

McGraw-Hill spokesman Jason Feuchtwanger said the cases were settled without any admission of liability or wrongdoing.

Ratings agencies came under intense scrutiny following the 2008 financial crisis for giving top-notch ratings to investments backed by subprime mortgages. As defaults and losses mounted in the housing market, especially among subprime loans, the value of bonds backed by the bad debt plummeted.

As the mortgage market collapsed, the ratings agencies sharply lowered their ratings on the investments.

With the value of such investments declining, funds that purchased the bonds filed for bankruptcy. King County and Abu Dhabi sued the ratings agencies and Morgan Stanley claiming the banks misled them about the safety of some investments that were part of a structured investment vehicle.

A structured investment vehicle is a fund that borrows money by issuing short-term securities at a low interest rate and then lends that money by purchasing long-term securities at higher interest. That process can make a profit for its investors from the difference.

Source: http://news.yahoo.com/moodys-p-settle-lawsuits-over-debt-ratings-194608758.html

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Wall Street Week Ahead: Central banks, data to steer investors

By Wanfeng Zhou

NEW YORK (Reuters) - With signs of a slower economy mounting, the near-term outlook for U.S. stocks isn't rosy, but investors may find comfort next week from the world's major central banks.

The Federal Reserve will meet on Tuesday and Wednesday, with the report of weaker-than-expected, first-quarter growth could reinforce expectations the Fed will keep purchasing bonds at a pace of $85 billion a month.

Low interest rates and ample liquidity provided by the Fed and other central banks have buoyed global equity markets because low borrowing costs for businesses and consumers lead to richer corporate profits. Major U.S. stock indexes hit record highs earlier this month.

"As long as it looks like central banks are on your side and on investors' side as far as providing more liquidity, that's going to help improve sentiment," said Brian Jacobsen, chief portfolio strategist at Wells Fargo Funds Management in Menomonee Falls, Wisconsin.

"I don't think (Fed officials) have got enough data since the last meeting to really justify changing policy. I really don't think they're going to look at slowing the pace of purchases until probably September."

A strong commitment from the Fed to continue its stimulative policy, coupled with corporate earnings that have mostly exceeded lowered forecasts, could help Wall Street extend a rally despite signs that the U.S. economic recovery is losing momentum.

Even though the market ended flat on Friday, its performance for the week was positive. The Standard & Poor's 500 rose 1.7 percent, the Dow Jones Industrial Average was up 1.1 percent and Nasdaq Composite Index rose 2.3 percent

The economy expanded at a 2.5 percent annual rate in the first quarter, the Commerce Department said on Friday, short of expectations of 3.0 percent and setting a cautious tone.

A heavy slate of key economic indicators will be released next week, including personal income and spending, the Institute for Supply Management's manufacturing and services activity indexes, pending home sales, the Chicago purchasing managers' index and consumer confidence from the Conference Board.

The highlight of the week will come on Friday when the Labor Department releases its employment report for April.

Economists polled by Reuters are looking for job growth of 150,000, up from 88,000 in March. The unemployment rate is likely to remain unchanged at 7.6 percent.

"Today's (GDP) data suggests maybe the momentum is much weaker that what was priced in," said John Praveen, chief investment strategist at Prudential International Investments Advisers in Newark, New Jersey.

"We have had a very strong rally, so people are looking for any trigger for profit-taking," he said. Praveen said the market could see a 5 percent pullback in the months ahead should upcoming data prove weaker than expected.

Stocks have had a wild run over the past week after hackers attacked the website of stock broker Charles Schwab Corp and a false report on the Associated Press's Twitter account about explosions at the White House sent the market into a brief tailspin.

On Thursday, a software glitch shut down the Chicago Board Options Exchange for half the day, preventing trading in options on two of the stock market's most closely watched indexes and delivering the latest blow to confidence in the way U.S. financial markets operate.

EUROPE, EARNINGS

The European Central Bank meets on Thursday and investors will watch to see if it delivers an interest-rate cut as the euro zone economy deteriorates further. Further monetary easing would encourage investors to buy riskier assets and boost stocks.

"The market has been rallying on the fact the ECB might actually start to do something; if the U.S. market reacts in the same way, that might get the market rallying," said John Canally, investment strategist and economist for LPL Financial in Boston.

With earnings reporting now half over, investors will look to see if companies can continue to exceed profit estimates despite lackluster revenue.

According to Thomson Reuters data, of the 271 companies in the S&P 500 that have reported earnings for the first quarter, 69 percent have beaten analysts' expectations, above the 63 percent average since 1994.

However, only 43.9 percent have topped analysts' revenue forecasts, well below the 62 percent average since 2002 and the 52 percent rate for the last four quarters.

Analysts now see earnings growth of 3.8 percent this quarter, up from expectations of 1.5 percent on April 1.

Next week Dow components reporting results will be Pfizer and Merck . Other companies scheduled to report include Loews Corp , Aetna Inc , Chesapeake Energy , Visa Inc , Viacom Inc and Kraft Foods Group Inc .

David Joy, chief market strategist at Ameriprise Financial, based in Boston where he helps oversee about $700 billion in assets, said the lackluster figures suggest the second quarter may not be as robust as hoped.

"Right now, markets are going through an adjustment process, trying to figure out just how robust the economy is here and overseas as well," Joy said. "You have investors sort of biding their time. They are invested, but not with complete conviction."

(Reporting By Wanfeng Zhou; Editing by Kenneth Barry)

Source: http://news.yahoo.com/wall-street-week-ahead-central-banks-data-steer-094959885.html

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Details of Boston carjacking victim's ordeal comes out in Globe interview



>> we will revisit this.

>>> chilling details surrounding the tsarnaev brothers alleged plot to attack the heart of new york city after causing so much damage in boston . according to city officials, the two marathon bombing suspects discussed driving to new york to detonate their remaining explosives in a spontaneous assault on times square . at the time, their arsenal included five pipe bombs and one pressure cooker bomb similar to the ones used in last monday's deadly attack. police say the younger brother had visited times square once last year but their plan fell apart after realizing the mercedes-benz car they hijacked did not have enough car to get to new york . a pre- miranda rights interrogation of 19-year-old dzhokhar tsarnaev it appears the younger brother has stopped answering questions about the bombing since he was read his rights on monday night and that has sparked a debate among lawmakers how the government should handle domestic terror cases.

>> we can't have, in a case like than, the judiciary deciding because it's on tv and it might look bad for them to allow the public safety exemption that is deemed legal by the united states supreme court that they would somehow intercede in this, it is confusing and it's horrible god awful policy and danger to the greater community and we have got to get to the bottom of this and we have got to fix it right now.

>> tsarnaev was reportedly questioned by investigators up to 16 hours over the course of two days and answering questions mostly in writing due to the severe injury to his neck.

>> jane harman , there would be some people that would look at the fact that the plot in times square was foiled because they didn't have enough gas in their tank to get down to new york as a sign -- as a good sign that this was half-baked plot. it actually scares me that guys -- this ill-prepared could be running around with bombs. it's the sort of thing you're not going to pick up chatter. you're not going to pick up any clues from overseas. this is a sort of a random violence that we should all really be child by even more so than if they had some contacts overseas.

>> i agree. mike hayden said the other day, the former director of the cia , that this is the new normal. in this case, i think we will learn that some mistakes were made. we should have been on these guys earlier than we were, but this type of thing, self-radicalized people, in this case, maybe this fellow misha had a lot to do with radicalizing these kids. self-radicalized people who go on the internet and you can find the recipe for building pressure cooker bombs or pipe bombs or other kinds of small weapons can maybe sometimes get lucky and pull it off in this country. they have to be right once. we have to be right 100% of the time but on something that mika said just before, joe, she said mike rogers , among other things, perhaps, are complaining that this fellow was mirandaized. a liberal named george will had an op-ed in "the washington post " yesterday talking about incarcerating the japanese during world war ii and made the point if we live by our values and we follow the rule of law, we do better and, in this case, i think when we look back on all of this, the way we handled the investigation and the prosecution of this fellow who for sure, i think based on the evidence we know who likely will be convicted, will be a model for the world and it will show people that we followed the rule of law here and that is what we have to do.

>> as congresswoman harmon is talking we are getting word that dzhokhar tsarnaev has been transported from beth israel hospital to prison. we are talking about his physical condition. apparently it's upgraded to the point they have taken him out of the hospital new and he has been moved to a prison in massachusetts. one of the people we haven't talked about a lot but we have heard about is this guy who was car-jacked a week ago. he is a 26-year-old chinese man in this black mercedes suv and come to boston to go to grad school and now working on a start-up. he lives in boston . he gets car-jacked around 11:00 last thursday night and taken on an interview with "the boston globe " a 90-minute ride. remember it was reported 30 minutes ? he says it's 90-minute ride. you have to talk about this key to these two brothers being caught. he said finally after this 90 minutes they realized they don't have enough gas to get to manhattan and pull up to a gas station and turns out it's cash only. so they have to go inside. one of the brothers has to go inside the gas station to pay. at that point, this guy who calls himself danny, didn't want to give his real name, makes a decision even though the other brother is in the back seat that is going to bolt. this is life and death . he unbuckles the seat belt and he said he ran in an angle that would be hard for the brother to shoot him. he runs across the street to another gas station and tells the attendant to call 911. he left his iphone in the car so it could be tracked and traced. it's a remarkable account if you have a chance to read "the boston globe " about two and a half hour interview where he gives a moment-by-moment recap and he is critical to these two guys being caught.

>> no doubt. that is when everything started unraveling for them and there was even the moment where his friend kept calling him up and he said if you speak in mandarin, i'm going to kill you right here. you get to the part where the brother was doing an english mandarin translation to tell him what to text back to his friend and the guy just kept his head and was responsible for these two terrorists being caught.

>> the reason the i phone was left in the car? the two brothers wanted to listen to music so he plugged in his iphone to the car.

>> oh, my lord!

>> so the phone was not on his body, it was plugged into the car.

>> runs across the street to a mob mobil station and they call 911.

>> it speaks to a new normal which congresswoman harman was touching on. i find your sentiment far more alarming than anything else. deval patrick , the governor, i thought handled it so well. he said the next day the young tsarnaev went to school and went to the gym and paertrtied with friends as if nothing had happen. going forward for law enforcement , how do you track this and what steps to prevent this from going forward? an e in the course challenge for law enforcement and intelligence officials going forward.

>> one of the tragedies, though, is president kennedy saw this. he said if someone wants to trade their life for mine, no way i can be protected. men with guns change history, whether it's sarajevo or memphis in 1968 . the day before, you broke in and you said this guy, these people are going to do than, everybody would go, come on, they could never pull this off, but they did.

>> jane?

>> yeah. the nypd has a lot of tools that other local police departments may have to learn about. of course, new york is a much bigger target and so is washington. perhaps than boston or someplace in the midwest. but they have a thousand intelligence officers . they have a huge police department . 35,000 people compared to 2,000 in boston . i think that's the number. obviously, a bigger population. but they can detect signs early. for example the older brother was thrown out of his mosque and there was behavior there they would pick up because they built trust with the muslim community . let's be clear that all would-be radicalized people are not muslim but nonetheless they can pick up signs and follow these people much more closely and they have thwarted a lot of plots. we have been successful more than we have failed in blocking plots against our country.

>> yes.

>> and these small bore plots, i know a lot of people were hurt but this is nothing like 9/11, are going to be in our future and if we have better intel in our local police departments, we're going to do better getting ahead of the curve, even with people like this who are substantially invisible.

>> jane harman , thank you so much. on monday, we will be marking six months since superstorm sandy devastated the eastern seaboard . we will be live from some of the hardest hit spots and see how they are recovering.

>>> coming up, mike florio will join us to break down the nfl draft .

>> thanks, willie.

>> trickalso chemical war fare in syria. richard haass weighs in on the significant developments in that conflict. chadwick boseman describes his role as the great jackie robinson .

>> great movie.

>> a new article "the atlantic" says changing technology means we may never run out of oil. james bennett is here to explain.

>> there you go!

>> the top stories coming up next and the political playbook.

>>> first, bill karins with a check on the forecast. bill?

>> good morning. it's a nice happy forecast for so many people in this country as we head to a nice, warm weekend for once. just about everywhere on the map. we are going to have some rain to deal with but first recap yesterday. one of the warmest days we have seen in montana, colorado through the central plains . it was beautiful. the last spot to warm up is minneapolis, north wards and up through the great lakes. that warm air coming your way this weekend. we do have a little bit of rain this morning. kansas city and st. louis that's going to head for louisville, nashville, memphis, little rock and tulsa during the day today so you need your umbrellas. tomorrow a lot of that rain will be in kentucky and tennessee. although it's warm, it will be, unfortunately, a little bit wet. here is your forecast into the weekend. starting with today, another great day from new york to boston to d.c. it is a little chilly in the northeast this morning but this afternoon, perfect. then the weekend forecast look at minneapolis. about time! 72 warm degrees! you're going to be the same temperature as atlanta because the southeast you're going to be dodging the raindrops all weekend long and maybe even a few thunderstorms mixed in too and wrap it up with your sunday forecast and notice kansas city , you deserve that after the spring you had. 74 and sunny beautiful degrees! overall, this is a thumb's up weekend. the only exception being the rain in the southeast. you're watching " morning joe ," brewed by starbucks.

Source: http://feeds.nbcnews.com/c/35002/f/653381/s/2b35495f/l/0Lvideo0Bmsnbc0Bmsn0N0Cid0C51672911/story01.htm

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Investorideas.com Newswire - Investing Ideas: Solar Stocks ...



Investing Ideas: Solar Stocks SolarCity (NasdaqGM: SCTY), EGing Photovoltaic (Shanghai: 600537.SS)

Ideas get bigger when you share them...

?

Point Roberts, WA - April 26, 2013 (Investorideas.com renewable energy newswire) Investorideas.com staff: Investorideas.com, an investor research portal specializing in investing ideas in leading sectors including renewable energy and solar stocks has added the following solar stocks to its directory of publicly traded companies in the sector to watch.

EGing Photovoltaic Technology Co.,Ltd ( Shanghai:600537.SS) is a high-tech company specialized in researching, developing, manufacturing and selling photovoltaic products. Its vertical integrated system combines ingot, wafer, cell, module packaging and solar power generation all together. EGing has the capacity of producing 1GW mono and poly silicon solar modules annually.

SolarCity Corporation ( NasdaqGM:SCTY) provides clean energy. The company has disrupted the century-old energy industry by providing renewable electricity directly to homeowners, businesses and government organizations for less than they spend on utility bills. SolarCity gives customers control of their energy costs to protect them from rising rates. The company offers solar power, energy efficiency and electric vehicle services, and makes clean energy easy by taking care of everything from design and permitting to monitoring and maintenance.?SolarCity currently serves 14 states and signs a new customer every five minutes.

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Saturday, April 27, 2013

Over 1,000 women sue Nuvaring maker over blood clots

A NuvaRing contraceptive. (Sandy Huffaker/Getty)Rachel Lietzke Payne started using NuvaRing in 2008, when she was a 20-year-old college student. The contraceptive device appealed to her because it was easy to use. Birth control pills have to be taken every day, but NuvaRing, which came onto the market in 2001, is inserted into the vagina and removed each month?and is just as effective at preventing pregnancy.

One Monday in October of 2010, more than a year after she first began using the vaginal ring, Payne met her father for a standing lunch date at Buffalo Wild Wings in Casselberry, north of where they lived in Orlando. When she and her dad walked out of the restaurant, Payne suddenly fell ill and spat up quarter-size chunks of blood onto the cement.

Payne was rushed to the hospital, where she spent 10 days being pumped with anticoagulants to thin her blood. She was diagnosed as having developed a blood clot in her lung, a condition that could have been fatal. ?It took them a while to figure out that it was blood clots, because I was 22 at the time,? said Payne, who is now a married 25-year-old aspiring air traffic controller with a toddler son. She was also a nonsmoker and fit, and she had no family history of blood clots, all potential risk factors.

But the doctors landed on what they believed might have caused the clotting: the NuvaRing.

Payne is now one of more than 1,000 women suing Merck & Co.?the pharmaceutical company that manufactures the birth control?in a federal district court in Missouri. They allege that the company?s device caused them to suffer blood clots?in a few cases, fatal ones?the risks of which they say they were inadequately warned about.

The suits are the latest in a pricey legal backlash over a variety of hormonal contraceptives that have come to the market in the past 10 years. Thousands of women sued over the Ortho Evra patch, citing studies that showed a higher blood clot risk compared to traditional birth control pills, costing Ortho McNeil, a Johnson & Johnson subsidiary, millions of dollars. And as of 2012, more than 10,000 suits had been filed against Bayer, the makers of Yaz and Yasmin birth control pills, which has set aside more than $1.5 billion to settle claims.

Roger Denton, the lead counsel for the multidistrict litigation against NuvaRing in Missouri, said he thinks the case could be as lucrative for his clients as Bayer?s litigation over Yaz and Yasmin. (Bayer has settled for an average of $216,000 with each plaintiff in that case.)

Hormonal contraceptives inhibit ovulation by releasing a combination of estrogen and progestin. While earlier iterations of progestin have shown only a slight increase in blood clot risk, recent studies have shown that newer forms of progestin?called third- and fourth-generation progestins, which were developed in the 1990s and 2000s?are associated with higher rates of blood clotting among women who take them compared to second-generation iterations of the hormone.

In fact, more than a dozen studies conducted over more than a decade have shown that women taking contraceptives containing a third-generation progestin?such as that used in NuvaRing and some birth control pills?have a 1.4 to 4 times higher risk of developing blood clots than women on contraceptives containing second-generation progestin.

The studies include a recent one funded by the FDA that tracked the health records of more than 835,000 women. It found that those who used the vaginal ring were more likely to experience venous thrombosis than women who took oral contraceptives. But the researchers warned that the finding is ?new and raises concern? and ?needs to be replicated in other studies.?

A handful of other studies, however, have shown no increased risk. Overall, the risk is still very low, with only around 6 to 10 out of 10,000 women developing blood clots over a year.

The plaintiffs in the NuvaRing case allege it's not just the hormone in the device that caused their blood clots, but also the delivery system. Unlike other forms of birth control, NuvaRing dispenses hormones directly into the bloodstream, which the plaintiffs' expert witness argues could cause "spikes" of hormones that make women more susceptible to blood clots. There's currently no large study that backs up that claim.

Some experts, however, warn that the results of the studies are being overblown by the media and trial lawyers, and may be scaring women away from effective birth control. More than 20 international researchers published an open letter in the Journal of Family Health and Reproductive Planning earlier this month saying the media and attorneys are creating a ?scare? that is not based on adequate research and could create more harm than good. They argue that large database studies, such as the one funded by the FDA, can be inaccurate because they don?t take into account all the confounding variables, such as obesity, that could affect blood clotting.

The letter notes that third- and fourth-generation hormonal contraceptives overall contain a very low risk of blood clots, and that more studies are needed before that risk can be determined. Overall, it notes, about 4 to 6 additional women out of every 10,000 on the newer forms of birth control would suffer a blood clot compared to women taking the older form of birth control. The risk of blood clotting goes up dramatically for pregnant women: 29 per 10,000 pregnant women develop a blood clot, meaning that the risks of unintended pregnancy are far greater than that of any hormonal birth control on the market.

The plaintiffs in the NuvaRing case say Merck did not adequately test or label the NuvaRing product to warn of these risks. Merck has disputed this, saying the company is confident its product is safe, and that it followed U.S. Food and Drug Administration guidelines for its packaging.

The company was awarded a judicial victory last week, when a judge in New Jersey threw out seven separate suits against NuvaRing, saying the plaintiffs did not prove that NuvaRing was the cause of their blood clots. New Jersey courts have tougher standards for suing an FDA-approved product than the federal court system, however, where some of the more than 1,000 suits face trial beginning in October.

?We are confident the company has provided appropriate and timely information about NuvaRing to consumers and the medical, scientific and regulatory communities,? Lainie Keller, a spokeswoman for Merck, said in a statement. ?We remain confident in the efficacy and safety profile of NuvaRing, and will continue to always act in the best interest of patients.?

But Denton, the lead attorney for the plaintiffs, said he?s sure his cases in the district court won?t be dismissed.

?That?s what all these drug companies say,? Denton said. ?'It?s good enough for the FDA, that?s the end of the story.? But under our law, that doesn?t matter. The jury decides.?

Source: http://news.yahoo.com/blogs/lookout/more-1-000-suits-against-nuvaring-trial-fall-103903135.html

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Friday, April 26, 2013

9/11 plane's landing gear discovered in NYC

NEW YORK (AP) ? A 5-foot-tall piece of landing gear believed to be from one of the planes destroyed in the Sept. 11 attacks has been discovered wedged between a mosque site and another building near the World Trade Center.

The part includes a clearly visible Boeing identification number, New York Police Department spokesman Paul Browne said Friday. The twisted, rusted metal part has cables and levers on it and is about 3 feet wide and 1.5 feet deep.

The piece of equipment was discovered Wednesday by surveyors inspecting the lower Manhattan site of a planned Islamic community center, at 51 Park Place, on behalf of the building's owner, police said. The inspectors called 911, and police secured the scene, documenting it with photos.

The spot where the landing gear was found is about three blocks from ground zero. When plans for the mosque and community center were first announced several years ago, opponents protested that putting a Muslim facility near ground zero showed disrespect. Supporters cited freedom of religion and said it wasn't too close to where Islamic extremists attacked on Sept. 11, 2001.

The medical examiner's office will complete a health and safety evaluation to determine whether to sift the soil around the buildings for possible human remains, police said.

Two hijacked planes slammed into the nearby World Trade Center towers in 2001, killing thousands of people.

Source: http://news.yahoo.com/part-9-11-planes-landing-gear-found-nyc-211517007.html

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Global stocks rise after surprise U.S. data, bonds fall

By Herbert Lash

NEW YORK (Reuters) - World stock markets rose and bond prices fell on Thursday as data indicated the U.S. labor market remains resilient despite recent signs of slower growth, while earnings that are beating lowered expectations helped buoy investor sentiment.

Wall Street opened higher, following gains in Europe, where markets were lifted on growing expectations that the European Central Bank will soon cut interest rates.

A report from the U.S. Labor Department said the number of Americans filing new claims for unemployment benefits fell last week by a surprisingly large 16,000.

The report appeared to counter several weeks of signs that U.S. economic activity softened in March and early April, a phenomenon that economists have dubbed the spring swoon because it has occurred the past two years.

Benchmark 10-year U.S. Treasury notes fell as much as 7/32 in price in reaction to the jobless claims figures. They last traded 2/32 lower to yield 1.7097 percent.

Recent weak global economic data, including record-high jobless figures from Spain on Thursday, has sparked expectations of more stimulus from central banks.

"Overall, investors see the potential for new measures and the distortion of global valuations as a reason to hold dogmatically onto their equities," said Guy Foster, head of portfolio strategy at Brewin Dolphin in London.

"Shares are seen as a yield asset class with risks skewed to the upside. Bonds have lost their appeal for the opposite reason."

U.S. stocks rose, boosted by gains in shares of materials companies, including iron ore producer Cliffs Natural Resources Inc ,

Cliffs jumped 15 percent to $20.95 after it posted earnings late on Wednesday that were much better than analysts had estimated. [ID:nL2N0DB2FF] The S&P 500 materials index <.splrcma> rose 1.04 percent.

The blended per-share growth estimate for earnings is now 3.6 percent, according to Thomson Reuters, up from 1.5 percent on April 1. The estimate is about half of recent quarters.

The Dow Jones industrial average <.dji> closed up 24.50 points, or 0.17 percent, at 14,700.80. The Standard & Poor's 500 Index <.spx> rose 6.37 points, or 0.40 percent, to 1,585.16. The Nasdaq Composite Index <.ixic> gained 20.33 points, or 0.62 percent, to 3,289.99.

"Investors coming into this earnings season were quite fearful, so even modestly positive news becomes great news, and that is what we've experienced for the last several days," said Lawrence Creatura, an equity portfolio manager at Federated Investors in Rochester, New York.

"It's probably a little early in the earnings season to talk about aggregate results, but it's important to recognize that earnings are growing and so higher prices are deserved," Creatura said.

Expectations of an ECB rate cut boosted shares and kept the euro near a three-week low to the dollar. Sources involved in the deliberations have told Reuters that momentum is building for monetary action to help the recession-hit euro zone.

The FTSE Eurofirst 300 index <.fteu3> index of top European shares rose 0.74 percent to close at ,200.64, near its peak of 1,209.05 it hit in mid-March.

MSCI's all-country world equity index <.miwd00000pus> gained 0.64 percent to 365.22.

The dollar rose against the euro as the U.S. labor market report allayed concerns about the pace of the economic recovery, with many analysts expecting the greenback to continue to gain.

The euro last traded at $1.3006, down 0.07 percent.

Against the yen, the dollar last traded at 99.37 yen, down 0.10 percent on the day.

Sterling jumped to a two-month high against the dollar and a three-month peak against the euro after data showed the UK economy comfortably avoided slipping back into recession in the first quarter.

UK gross domestic product rose 0.3 percent in the three months to March, well above forecasts of a 0.1 percent rise, as the economy bounced back after shrinking 0.3 percent at the end of 2012.

Brent crude oil prices rose above $103 a barrel, underpinned by a weaker dollar, while U.S. crude's discount to Brent fell below $10 for the first time since June 2012.

Brent crude rose $1.68 to settle at $103.41 a barrel.

U.S. crude gained $2.21 to settle at $93.64 a barrel.

(Additional reporting by Richard Hubbard in London, Editing by Dan Grebler and Jan Paschal)

Source: http://news.yahoo.com/asian-shares-tick-support-seen-global-monetary-stimulus-003433327--finance.html

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In a first, YouTube to showcase a week of comedy

NEW YORK (AP) ? For a week in May, YouTube will turn into the biggest open mic on the planet.

On Thursday, the Google Inc.-owned site will announce the YouTube Comedy Week, a seven-day cyber extravaganza designed to showcase some of the best comedy across its expansive video platform. From May 19-25, YouTube will be overrun with punch lines, sketches, stand-up routines and ? hopefully ? a lot of laughs.

It's the largest-scale attempt yet by YouTube to program its billions of hours of video and lead viewers to its growing channels of original programming. The video site is planning more event weeks around various themes to be held later this year and beyond.

"This has never been done before on YouTube," Danielle Tiedt, YouTube's vice president of marketing, said in an interview Wednesday ahead of the announcement. "I'm sure we'll learn a lot."

Comedy Week will kick off with a global live stream from Los Angeles' Culver Studios. Throughout the week, new episodes will debut from some of YouTube's most popular channels, comedians will perform and comics will curate lists of their favorite videos.

Among those participating are Sarah Silverman, Rainn Wilson, Michael Cera, Vince Vaughn and Seth Rogen. There will be new videos from Andy Samberg's Lonely Island troupe. Popular comedy destinations with channels on YouTube like The Onion, Nerdist, College Humor and Funny or Die will join in. And YouTube hopes its less famous users will also get in on the act.

The event is just the start of a new approach by YouTube to congregate its disparate stars ? from Hollywood professionals to Internet upstarts ? and to present a unified viewing experience for users. YouTube hopes the theme weeks will spotlight the original programming the site has invested hundreds of millions of dollars in to grow its platform as a kind of next-generation TV.

"We're hoping to do this in a pretty regular rhythm," said Tiedt. "You'll see several of these coming from us, for sure, as we highlight really big areas that we think are amazing areas of strength for YouTube."

The undertaking is months in the works. To executive-produce the weeklong event, YouTube brought in former "Jimmy Kimmel Live!" producer Daniel Kellison, whose production company, HaChaCha, recently launched two comedy YouTube channels: Jash and the Video Podcast Network. The kickoff live stream will be directed and produced by Joel Gallen, a veteran of the MTV Movie Awards.

Kellison says a staff of 40 has been assembled to help in what he calls the "tremendously daunting" task of organizing a sizable portion of the sprawling YouTube realm.

"It's a massive undertaking," he says. "If you try to organize it all and figure it all out, you'll drown. It's not possible. We're just doing the best we can in trying to produce this."

A few missteps are inevitable, Kellison says. But the plan isn't to put on a slickly produced show, but something more lo-fi and relaxed.

"We've been able to go to all these comedians and say, 'Hey, we can do whatever we want and have fun doing it,'" says Kellison. "It's taken on this sort of comedy Woodstock type of vibe."

The duo of Eric Wareheim and Tim Heidecker, known as Tim & Eric, will be performing in the festivities. Wareheim, among the founders of Jash, believes Comedy Week will help raise the bar for comedy on YouTube.

"It's going to be higher production value, everyone taking it a little bit more serious rather than a throwaway Internet short ? make it a place where legitimate stuff can be and change the perception of what YouTube can be," Wareheim says. "Tim and I have been using YouTube for our TV shows, our movies ? for everything ? to kind of promote stuff. Now instead of just as a promotional tool, we're using it to really distribute content."

Getting even a segment of YouTube to synchronize would seem a tall order. But marshaling together Comedy Week reminds Kellison of the chaotic first night of "Jimmy Kimmel Live!"

"We had Coldplay on the outdoor stage; Warren Sapp coming in after he won the Super Bowl on a helicopter; Jon Gruden canceling; the fire marshal trying to shut us down; Snoop Dogg with the death threats; and a buzzed George Clooney," he recalls. "I imagine this will be very similar."

___

Follow AP Entertainment Writer Jake Coyle on Twitter at: http://twitter.com/jake_coyle

Source: http://news.yahoo.com/first-youtube-showcase-week-comedy-120037906.html

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ALS trial shows novel therapy is safe

Wednesday, April 24, 2013

An investigational treatment for an inherited form of Lou Gehrig's disease has passed an early phase clinical trial for safety, researchers at Washington University School of Medicine in St. Louis and Massachusetts General Hospital report.

The researchers have shown that the therapy produced no serious side effects in patients with the disease, also known as amyotrophic lateral sclerosis (ALS). The phase 1 trial's results, available online in Lancet Neurology, also demonstrate that the drug was successfully introduced into the central nervous system.

The treatment uses a technique that shuts off the mutated gene that causes the disease. This approach had never been tested against a condition that damages nerve cells in the brain and spinal cord.

"These results let us move forward in the development of this treatment and also suggest that it's time to think about applying this same approach to other mutated genes that cause central nervous system disorders," says lead author Timothy Miller, MD, PhD, assistant professor of neurology at Washington University. "These could include some forms of Alzheimer's disease, Parkinson's disease, Huntington's disease and other conditions."

ALS destroys nerves that control muscles, gradually leading to paralysis and death. For treatment of the disease, the sole FDA-approved medication, Riluzole, has only a marginal effect.

Most cases of ALS are sporadic, but about 10 percent are linked to inherited mutations. Scientists have identified changes in 10 genes that can cause ALS and are still looking for others.

The study focused on a form of ALS caused by mutations in a gene called SOD1, which account for 2 percent of all ALS cases. Researchers have found more than 100 mutations in the SOD1 gene that cause ALS.

"At the molecular level, these mutations affect the properties of the SOD1 protein in a variety of ways, but they all lead to ALS," says Miller, who is director of the Christopher Wells Hobler Lab for ALS Research at the Hope Center for Neurological Disorders at Washington University.

Rather than try to understand how each mutation causes ALS, Miller and his colleagues focused on blocking production of the SOD1 protein using a technique called antisense therapy.

To make a protein, cells have to copy the protein-building instructions from the gene. Antisense therapy blocks the cell from using these copies, allowing researchers to selectively silence individual genes.

"Antisense therapy has been considered and tested for a variety of disorders over the past several decades," Miller says. "For example, the FDA recently approved an antisense therapy called Kynamro for familial hypercholesterolemia, an inherited condition that increases cholesterol levels in the blood."

Miller and colleagues at the University of California-San Diego devised an antisense drug for SOD1 and successfully tested it in an animal model of the disease.

Merit Cudkowicz, MD, chief of neurology at Massachusetts General Hospital, was co-PI of the phase I clinical safety trial described in the new paper. Clinicians at Barnes-Jewish Hospital, Massachusetts General Hospital, Johns Hopkins Hospital and the Methodist Neurological Institute in Houston gave antisense therapy or a placebo to 21 patients with SOD1-related ALS. Treatment consisted of spinal infusions that lasted 11 hours.

The scientists found no significant difference between side effects in the control and treatment groups. Headache and back pain, both of which are often associated with spinal infusion, were among the most common side effects.

Immediately after the injections, the researchers took spinal fluid samples. This let them confirm the antisense drug was circulating in the spinal fluid of patients who received the treatment.

To treat SOD1-related ALS in the upcoming phase II trial, researchers will need to increase the dosage of the antisense drug. As the dose rises, they will watch to ensure that the therapy does not cause harmful inflammation or other side effects as it lowers SOD1 protein levels.

"All the information that we have so far suggests lowering SOD1 will be safe," Miller says. "In fact, completely disabling SOD1 in mice seems to have little to no effect. We think it will be OK in patients, but we won't know for sure until we've conducted further trials."

The therapy may one day be helpful in the more common, noninherited forms of ALS, some of which may be linked to problems with the SOD1 protein.

"Before we can consider using this same therapy for sporadic ALS, we need more evidence that SOD1 is a major contributor to these forms of the disorder," Miller says.

###

Washington University School of Medicine: http://www.medicine.wustl.edu

Thanks to Washington University School of Medicine for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

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Source: http://www.labspaces.net/127890/ALS_trial_shows_novel_therapy_is_safe

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Thursday, April 25, 2013

Roundworm quells obesity and related metabolic disorders

Apr. 25, 2013 ? Researchers at the University of Maryland School of Medicine, Baltimore, have shown in a mouse model that infection with nematodes (also known as roundworms) can not only combat obesity but ameliorate related metabolic disorders. Their research is published ahead of print online in the journal Infection and Immunity.

Gastrointestinal nematodes infect approximately 2 billion people worldwide, and some researchers believe up until the 20th century almost everyone had worms. In developed countries there is a decreasing incidence of nematode infection but a rising prevalence of certain types of autoimmunity, suggesting a relationship between the two. Nematode infection has been purported to have therapeutic effects and currently clinical trials are underway to examine worms as a treatment for diseases associated with the relevant cytokines, including inflammatory bowel disease, multiple sclerosis, and allergies.

In the study researchers tested the effect of nematode infection on mice fed a high-fat diet. Infected mice of normal girth gained 15 percent less weight than those that were not infected. Mice that were already obese when infected lost roughly 13 percent of their body weight within 10 days. Infection also drastically lowered fasting blood glucose, a risk factor for diabetes, and reduced fatty liver disease, decreasing liver fat by ~25 percent, and the weight of the liver by 30 percent.

The levels of insulin and leptin also dropped, "indicating that the mice restored their sensitivities to both hormones," says corresponding author Aiping Zhao of the University of Maryland School of Medicine, Baltimore. Leptin moderates appetite. As with too much insulin, too high a level of leptin results in insensitivity, thus contributing to obesity and metabolic syndrome, Zhao explains.

The mechanism of the moderation of these hormones "was associated with a parasite-induced reduction in glucose absorption in the intestine, reduced liver triglycerides, and an increase in the population of cells called "alternatively activated macrophages," which regulate glucose metabolism and inflammation," says coauthor Joe Urban of the United States Department of Agriculture. Some of these changes involved "a protein called interleukin-13 and related intracellular signaling mechanisms," he says. "This suggests that there are immune related shifts in metabolism that can alter expression of obesity and related metabolic syndrome."

The incidence of obesity has been climbing dramatically, worldwide. It is a key risk factor for many metabolic diseases, including diabetes, hypertension, and heart disease. Recent studies indicate that it is accompanied by chronic low-grade inflammation in adipose tissues, causing the release of proinflammatory cytokines and chemokines that contribute to the development of cardiovascular disease and metabolic syndrome.

Parasitic nematode infection induces a marked elevation in host immune Th2-cells and related type 2 cytokines which, besides combating the infection, also have potent anti-inflammatory activity, according to the report.

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The above story is reprinted from materials provided by American Society for Microbiology, via EurekAlert!, a service of AAAS.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Z. Yang, V. Grinchuk, A. Smith, B. Qin, J. A. Bohl, R. Sun, L. Notari, Z. Zhang, H. Sesaki, J. F. Urban, T. Shea-Donohue, A. Zhao. Parasitic Nematode-Induced Modulation of Body Weight and Associated Metabolic Dysfunction in Mouse Models of Obesity. Infection and Immunity, 2013; DOI: 10.1128/IAI.00053-13

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/BtOQmRTqrHQ/130425164504.htm

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Workplace stress poses risk to health

Apr. 23, 2013 ? Stressful situations at work can have a negative impact on the cardiovascular system and the metabolism. Stress, which is transmitted by direct and indirect signaling pathways, leads to an inflammatory response in the body, which can trigger cardiovascular diseases, amongst others.

These results, which were achieved by scientists from the Helmholtz Zentrum M?nchen following their evaluation of data from a population-based cohort study, were published in the specialist journals Brain, Behavior, and Immunity and Psychosomatic Medicine.

The study is based on a long-term observation of more than 950 people as part of the population-based cohort study MONICA/KORA. The work was conducted by Dr. Rebecca Emeny as part of the Mental Health working group headed by Prof. Karl-Heinz Ladwig, Institute of Epidemiology II (EPI II) at the Helmholtz Zentrum M?nchen (HMGU). Data was analyzed from questionnaires on psychological stress at work and concentrations of inflammatory biomarkers in the blood. The results showed that healthy workers who were exposed to stress at work displayed significantly elevated inflammatory parameters and faced twice the risk of cardiovascular diseases.

More than half of the participants in the study stated that they experienced psychological strain and stress at work. Stress is regarded as a cardiovascular risk factor. Its consequences are communicated directly via activated messenger substances as well as indirectly via unhealthy stress-related behavior. In particular, the scientists found a clear association between stress and elevated concentrations of CRP (C-reactive protein), which is an inflammatory marker, and were thus able to demonstrate a stress-related inflammatory reaction in the body. Moreover, job stress led to harmful psychological effects such as depression and sleep disturbances as well as to unhealthy behavior, for example, physical inactivity. Doing sports regularly, for at least one hour per week, significantly reduced inflammatory activity. However, the differences in terms of health risks between people who suffered from work stress and those who did not still remained.

With their analysis, the scientists at HMGU have made a substantial contribution towards a deeper understanding of stress-related responses in the body. "The insights gained from this study form important starting points for finding preventive measures that will protect against stress-related diseases such as coronary heart disease," says Dr. Emeny, first author of the study.

Environmental factors and lifestyle play a major role in the development of common diseases in Germany such as cardiovascular diseases and diabetes mellitus. The aim of the Helmholtz Zentrum M?nchen is to develop new approaches for the diagnosis, therapy and prevention of the most common diseases.

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Story Source:

The above story is reprinted from materials provided by Helmholtz Zentrum Muenchen - German Research Centre for Environmental Health.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal References:

  1. Rebecca Emeny, Marie-Elena Lacruz, Jens Baumert, Astrid Zierer, Alexander von Eisenhart Rothe, Christine Autenrieth, Christian Herder, Wolfgang Koenig, Barbara Thorand, Karl-Heinz Ladwig. Job strain associated CRP is mediated by leisure time physical activity: Results from the MONICA/KORA study. Brain, Behavior, and Immunity, 2012; 26 (7): 1077 DOI: 10.1016/j.bbi.2012.07.004
  2. Emeny, R.T. et al. Contributions of Job Strain and 9 Emerging Biomarkers of Coronary Events in Healthy Workers: the MONICA/KORA Augsburg Case-Cohort. Psychosomatic Medicine, 75(3):317-25

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/mind_brain/mental_health/~3/uVpg6C8YPCY/130423090940.htm

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NBCUniversal expansion to start with Harry Potter

(AP) ? NBCUniversal plans to begin construction this summer on a $1.6 billion, 25-year expansion of its Los Angeles-area theme park, offices and production facilities.

The company owned by Comcast Corp. announced Tuesday that it would start building The Wizarding World of Harry Potter at its Universal Studios Hollywood theme park, along with upgraded TV production studios and office space on the studio lot.

The project would eventually include a hotel and retail outlets, adding nearly 2 million square feet to the studio complex. The plan initially called for nearly 3,000 residences, but that was dropped last year after objections from local residents and politicians.

The Los Angeles County Board of Supervisors tentatively approved the plan Tuesday, unanimously directing its lawyers to prepare documents for final approval.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/4e67281c3f754d0696fbfdee0f3f1469/Article_2013-04-23-NBCUniversal%20Studio%20Complex/id-54ca49edb83048129e4be6d5a4b54ee9

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Selena Gomez: I'm Young! Having Fun!

Source: http://www.thehollywoodgossip.com/2013/04/selena-gomez-im-young-having-fun/

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Wednesday, April 24, 2013

Slow is scary if France quits nuclear : state institute

By Marion Douet

TOURNEMIRE, France (Reuters) - A long slow retreat from nuclear power in France or indecision over policy could be very risky as skilled staff retire and young people reject careers with an uncertain future, the state-funded atomic safety research institute said.

If France does decide to pull out of atomic energy it should follow Germany's example and do it quickly, or face operating with inadequate personnel, said Jacques Repussard, who heads the Institute for Radiological Protection and Nuclear Safety (IRSN).

"You can't spread the exit of nuclear over half a century. It's very dangerous," he said, adding that this consideration partly explained Germany's decision to opt for a fast exit to avoid a loss of skills.

France's state-owned utility EDF, which operates its 58 nuclear reactors, faces a wave of retirements and will have to replace half its nuclear staff by 2017-18.

While Socialist President Francois Hollande has undertaken to cut the country's reliance on atomic energy to 50 percent of electricity consumption by 2025, from 75 percent now, he has not made clear what would happen after that date.

"If, in the next 10 years, there is no clarity on what the future of nuclear energy will be, we will inevitably see a trend in our universities of young people saying: 'I don't want to do that line of work'," Repussard told Reuters in an interview at one of its research centers in the south of France.

As part of the reduction drive in France, the world's most nuclear-reliant country, the government has announced that Fessenheim in the east, its oldest nuclear plant, will shut by the end of 2016.

While the government has allowed EDF to pursue building its first next-generation nuclear reactor in Flamanville in northwestern France, it abandoned the previous government's project to build another reactor at Penly in Normandy.

Germany decided to shut all its nuclear reactors by 2022, in a policy reversal drafted in a rush after Japan's Fukushima disaster in March 2011.

CONSIDERABLE RISKS

"It was criticized and we asked ourselves how they would do it... But it's wise because doing it slowly means taking considerable risks with the last operating reactors, as finding skilled subcontractors and companies manufacturing certain parts (could become problematic)," Repussard said.

But he admitted that France, where nuclear reactors are on average 26 years old, would never consider a fast exit even though this would be the safest approach if it decided to stop building new reactors or conducting research.

Another issue for the government to consider, he said, was that generic defects would probably appear in several reactors at around the same time, leading them to stop working abruptly.

This echoed comments earlier this month by Pierre-Franck Chevet, the head of France's nuclear safety agency, who said the country needed to ensure there was enough available electricity generation capacity to cope with the sudden outage of 5 to 10 nuclear reactors.

"One day we will see wear and tear appear in the steel of core tanks... and when we see it in one, we will probably see it in all the reactors of the same generation in a short space of time," Repussard said.

Electrabel, the Belgian subsidiary of GDF Suez, has had to close two reactors in Belgium after finding possible cracks in the core tanks that house them.

"To be 80 percent reliant on nuclear energy exposes us to that kind of situation," he added.

(Writing by Muriel Boselli; Editing by Anthony Barker)

Source: http://news.yahoo.com/slow-scary-france-quits-nuclear-state-institute-154437859--finance.html

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